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NF-κB suppresses apoptosis and promotes bladder cancer cell proliferation by upregulating survivin expression in vitro and in vivo

Nuclear factor kappa-B (NF-κB) activation is a common phenomenon in cancers, which results in the aberrant expression of NF-κB target genes and leads to malignant transformation, metastatic dissemination, abnormal cell proliferation or resistance to cell death. Survivin is a unique member of the IAP...

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Detalles Bibliográficos
Autores principales: Cui, Xiaolu, Shen, Dezhi, Kong, Chuize, Zhang, Zhe, Zeng, Yu, Lin, Xuyong, Liu, Xiankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282527/
https://www.ncbi.nlm.nih.gov/pubmed/28139689
http://dx.doi.org/10.1038/srep40723