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Chitosan functionalized nanocochleates for enhanced oral absorption of cyclosporine A

It remains a significant challenge to overcome the poor permeability of cyclosporine A and enhance its oral absorption. In this study, we have identified a positively charged chitosan that is able to induce coiling up of anionic lipids to form nanocochleates with an average size of 114.2 ± 0.8 nm, w...

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Detalles Bibliográficos
Autores principales:	Liu, Min, Zhong, Xiaoming, Yang, Zhiwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282608/ https://www.ncbi.nlm.nih.gov/pubmed/28112262 http://dx.doi.org/10.1038/srep41322

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