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Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin

BACKGROUND: The multiligand receptor megalin controls the brain uptake of a number of ligands, including insulin and leptin. Despite the role of megalin in the transport of these metabolically relevant hormones, the role of megalin at the blood–brain-barrier (BBB) has not yet been explored in the co...

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Detalles Bibliográficos
Autores principales: Bartolome, Fernando, Antequera, Desiree, Tavares, Eva, Pascual, Consuelo, Maldonado, Rosario, Camins, Antoni, Carro, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282716/
https://www.ncbi.nlm.nih.gov/pubmed/28143489
http://dx.doi.org/10.1186/s12974-017-0800-2