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Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin
BACKGROUND: The multiligand receptor megalin controls the brain uptake of a number of ligands, including insulin and leptin. Despite the role of megalin in the transport of these metabolically relevant hormones, the role of megalin at the blood–brain-barrier (BBB) has not yet been explored in the co...
Autores principales: | Bartolome, Fernando, Antequera, Desiree, Tavares, Eva, Pascual, Consuelo, Maldonado, Rosario, Camins, Antoni, Carro, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282716/ https://www.ncbi.nlm.nih.gov/pubmed/28143489 http://dx.doi.org/10.1186/s12974-017-0800-2 |
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