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Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial

BACKGROUND: Adequate pain relief at the point of injury and during transport to hospital is a major challenge in all acute traumas, especially for those with hip fractures, whose injuries are difficult to immobilise and whose long-term outcomes may be adversely affected by administration of opiate a...

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Autores principales: Bulger, Jenna K., Brown, Alan, Evans, Bridie A., Fegan, Greg, Ford, Simon, Guy, Katy, Jones, Sian, Keen, Leigh, Khanom, Ashrafunnesa, Pallister, Ian, Rees, Nigel, Russell, Ian T., Seagrove, Anne C., Snooks, Helen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282771/
https://www.ncbi.nlm.nih.gov/pubmed/28163926
http://dx.doi.org/10.1186/s40814-016-0115-6
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author Bulger, Jenna K.
Brown, Alan
Evans, Bridie A.
Fegan, Greg
Ford, Simon
Guy, Katy
Jones, Sian
Keen, Leigh
Khanom, Ashrafunnesa
Pallister, Ian
Rees, Nigel
Russell, Ian T.
Seagrove, Anne C.
Snooks, Helen A.
author_facet Bulger, Jenna K.
Brown, Alan
Evans, Bridie A.
Fegan, Greg
Ford, Simon
Guy, Katy
Jones, Sian
Keen, Leigh
Khanom, Ashrafunnesa
Pallister, Ian
Rees, Nigel
Russell, Ian T.
Seagrove, Anne C.
Snooks, Helen A.
author_sort Bulger, Jenna K.
collection PubMed
description BACKGROUND: Adequate pain relief at the point of injury and during transport to hospital is a major challenge in all acute traumas, especially for those with hip fractures, whose injuries are difficult to immobilise and whose long-term outcomes may be adversely affected by administration of opiate analgesics. Fascia iliaca compartment block (FICB) is a procedure routinely undertaken by doctors and nurses in the emergency department for patients with hip fracture but not yet evaluated for use by paramedics at the scene of emergency calls. In this feasibility study, we aim to test whether FICB administered by paramedics at the scene of participants’ hip fractures is feasible, safe and acceptable. This will enable us to decide whether to proceed to a fully powered, multi-centre pragmatic randomised trial to evaluate whether the procedure is effective for patients and worthwhile for the NHS. METHODS/DESIGN: In this study, we propose to recruit ten paramedics in an urban area of South Wales. We will train them to carry out FICB when they attend patients with hip fracture. We will randomly allocate eligible patients to FICB or usual care using audited scratch cards. We will follow up participants to assess measurability of key outcomes including quality of life, pain scores, adverse events, length of stay in hospital, acceptability to patients and compliance of paramedics. We will assess whether the findings meet specified feasibility criteria and, if so, plan a full trial. DISCUSSION: This study will enable us to recommend whether to undertake a definitive trial of FICB by paramedics for hip fracture. TRIAL REGISTRATION: ISRCTN60065373
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spelling pubmed-52827712017-02-03 Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial Bulger, Jenna K. Brown, Alan Evans, Bridie A. Fegan, Greg Ford, Simon Guy, Katy Jones, Sian Keen, Leigh Khanom, Ashrafunnesa Pallister, Ian Rees, Nigel Russell, Ian T. Seagrove, Anne C. Snooks, Helen A. Pilot Feasibility Stud Study Protocol BACKGROUND: Adequate pain relief at the point of injury and during transport to hospital is a major challenge in all acute traumas, especially for those with hip fractures, whose injuries are difficult to immobilise and whose long-term outcomes may be adversely affected by administration of opiate analgesics. Fascia iliaca compartment block (FICB) is a procedure routinely undertaken by doctors and nurses in the emergency department for patients with hip fracture but not yet evaluated for use by paramedics at the scene of emergency calls. In this feasibility study, we aim to test whether FICB administered by paramedics at the scene of participants’ hip fractures is feasible, safe and acceptable. This will enable us to decide whether to proceed to a fully powered, multi-centre pragmatic randomised trial to evaluate whether the procedure is effective for patients and worthwhile for the NHS. METHODS/DESIGN: In this study, we propose to recruit ten paramedics in an urban area of South Wales. We will train them to carry out FICB when they attend patients with hip fracture. We will randomly allocate eligible patients to FICB or usual care using audited scratch cards. We will follow up participants to assess measurability of key outcomes including quality of life, pain scores, adverse events, length of stay in hospital, acceptability to patients and compliance of paramedics. We will assess whether the findings meet specified feasibility criteria and, if so, plan a full trial. DISCUSSION: This study will enable us to recommend whether to undertake a definitive trial of FICB by paramedics for hip fracture. TRIAL REGISTRATION: ISRCTN60065373 BioMed Central 2017-01-23 /pmc/articles/PMC5282771/ /pubmed/28163926 http://dx.doi.org/10.1186/s40814-016-0115-6 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Study Protocol
Bulger, Jenna K.
Brown, Alan
Evans, Bridie A.
Fegan, Greg
Ford, Simon
Guy, Katy
Jones, Sian
Keen, Leigh
Khanom, Ashrafunnesa
Pallister, Ian
Rees, Nigel
Russell, Ian T.
Seagrove, Anne C.
Snooks, Helen A.
Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial
title Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial
title_full Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial
title_fullStr Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial
title_full_unstemmed Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial
title_short Rapid analgesia for prehospital hip disruption (RAPID): protocol for feasibility study of randomised controlled trial
title_sort rapid analgesia for prehospital hip disruption (rapid): protocol for feasibility study of randomised controlled trial
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282771/
https://www.ncbi.nlm.nih.gov/pubmed/28163926
http://dx.doi.org/10.1186/s40814-016-0115-6
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