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Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice
BACKGROUND: Synucleinopathies such as Parkinson’s disease or multiple system atrophy are characterized by Lewy bodies in distinct brain areas. These aggregates are mainly formed by α-synuclein inclusions, a protein crucial for synaptic functions in the healthy brain. Transgenic animal models of synu...
Autores principales: | Rabl, R., Breitschaedel, C., Flunkert, S., Duller, S., Amschl, D., Neddens, J., Niederkofler, V., Rockenstein, E., Masliah, E., Roemer, H., Hutter-Paier, B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282838/ https://www.ncbi.nlm.nih.gov/pubmed/28143405 http://dx.doi.org/10.1186/s12868-017-0341-8 |
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