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Merkel cell carcinoma occurring in a black woman: a case report

BACKGROUND: Merkel cell carcinoma is a rare, very aggressive neuroectodermal tumor of the skin. It is typically located on sun-exposed skin and frequently found in white men aged between 70 and 80 years. CASE PRESENTATION: We report a case of a 58-year-old black woman diagnosed with Merkel cell carc...

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Autores principales: Kadiri, Selma, Aissa, Abdellah, Berhili, Soufiane, Khmou, Mouna, Elmajjaoui, Sanaa, Kebdani, Tayeb, El Khannoussi, Basma, Elkacemi, Hanan, Benjaafar, Noureddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282901/
https://www.ncbi.nlm.nih.gov/pubmed/28143624
http://dx.doi.org/10.1186/s13256-016-1189-8
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author Kadiri, Selma
Aissa, Abdellah
Berhili, Soufiane
Khmou, Mouna
Elmajjaoui, Sanaa
Kebdani, Tayeb
El Khannoussi, Basma
Elkacemi, Hanan
Benjaafar, Noureddine
author_facet Kadiri, Selma
Aissa, Abdellah
Berhili, Soufiane
Khmou, Mouna
Elmajjaoui, Sanaa
Kebdani, Tayeb
El Khannoussi, Basma
Elkacemi, Hanan
Benjaafar, Noureddine
author_sort Kadiri, Selma
collection PubMed
description BACKGROUND: Merkel cell carcinoma is a rare, very aggressive neuroectodermal tumor of the skin. It is typically located on sun-exposed skin and frequently found in white men aged between 70 and 80 years. CASE PRESENTATION: We report a case of a 58-year-old black woman diagnosed with Merkel cell carcinoma of the posterior face of the right elbow. She had biopsy excision and was lost to follow-up. Four months later, she presented with recurrent disease on the inferior third of the right arm with three ipsilateral axillary lymph node metastases. Amputation of the right arm and ipsilateral axillary lymph node dissection were performed, followed by adjuvant radiotherapy. Six months later, the patient died as a result of respiratory failure caused by lung metastasis. To the best of our knowledge, no specific studies have been done comparing the course and the characteristics of Merkel cell carcinoma in white and black populations, and no similar case has been reported in the literature. CONCLUSIONS: The Merkel cell carcinoma is very rare in black people. As described elsewhere in the literature, our patient had a poor outcome despite radical management. To date, to the best of our knowledge, there has been no comparison of the prognosis of this tumor in white and black populations.
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spelling pubmed-52829012017-02-03 Merkel cell carcinoma occurring in a black woman: a case report Kadiri, Selma Aissa, Abdellah Berhili, Soufiane Khmou, Mouna Elmajjaoui, Sanaa Kebdani, Tayeb El Khannoussi, Basma Elkacemi, Hanan Benjaafar, Noureddine J Med Case Rep Case Report BACKGROUND: Merkel cell carcinoma is a rare, very aggressive neuroectodermal tumor of the skin. It is typically located on sun-exposed skin and frequently found in white men aged between 70 and 80 years. CASE PRESENTATION: We report a case of a 58-year-old black woman diagnosed with Merkel cell carcinoma of the posterior face of the right elbow. She had biopsy excision and was lost to follow-up. Four months later, she presented with recurrent disease on the inferior third of the right arm with three ipsilateral axillary lymph node metastases. Amputation of the right arm and ipsilateral axillary lymph node dissection were performed, followed by adjuvant radiotherapy. Six months later, the patient died as a result of respiratory failure caused by lung metastasis. To the best of our knowledge, no specific studies have been done comparing the course and the characteristics of Merkel cell carcinoma in white and black populations, and no similar case has been reported in the literature. CONCLUSIONS: The Merkel cell carcinoma is very rare in black people. As described elsewhere in the literature, our patient had a poor outcome despite radical management. To date, to the best of our knowledge, there has been no comparison of the prognosis of this tumor in white and black populations. BioMed Central 2017-01-31 /pmc/articles/PMC5282901/ /pubmed/28143624 http://dx.doi.org/10.1186/s13256-016-1189-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Kadiri, Selma
Aissa, Abdellah
Berhili, Soufiane
Khmou, Mouna
Elmajjaoui, Sanaa
Kebdani, Tayeb
El Khannoussi, Basma
Elkacemi, Hanan
Benjaafar, Noureddine
Merkel cell carcinoma occurring in a black woman: a case report
title Merkel cell carcinoma occurring in a black woman: a case report
title_full Merkel cell carcinoma occurring in a black woman: a case report
title_fullStr Merkel cell carcinoma occurring in a black woman: a case report
title_full_unstemmed Merkel cell carcinoma occurring in a black woman: a case report
title_short Merkel cell carcinoma occurring in a black woman: a case report
title_sort merkel cell carcinoma occurring in a black woman: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282901/
https://www.ncbi.nlm.nih.gov/pubmed/28143624
http://dx.doi.org/10.1186/s13256-016-1189-8
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