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The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia reperfusion injury in mice

Acute kidney injury (AKI) caused by ischemia reperfusion is a major clinical problem in both native and transplanted kidneys. We previously showed that deficiency of Nrf2, a potent bZIP transcription factor that binds to the antioxidant response element, enhances susceptibility to experimental ische...

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Detalles Bibliográficos
Autores principales:	Liu, Manchang, Reddy, Narsa M., Higbee, Elizabeth M., Potteti, Haranatha R., Noel, Sanjeev, Racusen, Lorraine, Kensler, Thomas W., Sporn, Michael B., Reddy, Sekhar P., Rabb, Hamid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282962/ https://www.ncbi.nlm.nih.gov/pubmed/24088953 http://dx.doi.org/10.1038/ki.2013.357

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