Cargando…
Thyroid Stimulating Hormone Receptor
Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283706/ https://www.ncbi.nlm.nih.gov/pubmed/28117293 http://dx.doi.org/10.4274/2017.26.suppl.10 |
_version_ | 1782503536913809408 |
---|---|
author | Tuncel, Murat |
author_facet | Tuncel, Murat |
author_sort | Tuncel, Murat |
collection | PubMed |
description | Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role in tumor growth, which is initiated by several oncogenes. This article will provide a brief review of TSHR and related diseases. |
format | Online Article Text |
id | pubmed-5283706 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Galenos Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-52837062017-03-27 Thyroid Stimulating Hormone Receptor Tuncel, Murat Mol Imaging Radionucl Ther Review Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role in tumor growth, which is initiated by several oncogenes. This article will provide a brief review of TSHR and related diseases. Galenos Publishing 2017-02 2017-01-09 /pmc/articles/PMC5283706/ /pubmed/28117293 http://dx.doi.org/10.4274/2017.26.suppl.10 Text en © Molecular Imaging and Radionuclide Therapy, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Tuncel, Murat Thyroid Stimulating Hormone Receptor |
title | Thyroid Stimulating Hormone Receptor |
title_full | Thyroid Stimulating Hormone Receptor |
title_fullStr | Thyroid Stimulating Hormone Receptor |
title_full_unstemmed | Thyroid Stimulating Hormone Receptor |
title_short | Thyroid Stimulating Hormone Receptor |
title_sort | thyroid stimulating hormone receptor |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283706/ https://www.ncbi.nlm.nih.gov/pubmed/28117293 http://dx.doi.org/10.4274/2017.26.suppl.10 |
work_keys_str_mv | AT tuncelmurat thyroidstimulatinghormonereceptor |