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Thyroid Stimulating Hormone Receptor

Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not...

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Detalles Bibliográficos
Autor principal: Tuncel, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283706/
https://www.ncbi.nlm.nih.gov/pubmed/28117293
http://dx.doi.org/10.4274/2017.26.suppl.10
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author Tuncel, Murat
author_facet Tuncel, Murat
author_sort Tuncel, Murat
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description Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role in tumor growth, which is initiated by several oncogenes. This article will provide a brief review of TSHR and related diseases.
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spelling pubmed-52837062017-03-27 Thyroid Stimulating Hormone Receptor Tuncel, Murat Mol Imaging Radionucl Ther Review Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role in tumor growth, which is initiated by several oncogenes. This article will provide a brief review of TSHR and related diseases. Galenos Publishing 2017-02 2017-01-09 /pmc/articles/PMC5283706/ /pubmed/28117293 http://dx.doi.org/10.4274/2017.26.suppl.10 Text en © Molecular Imaging and Radionuclide Therapy, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Tuncel, Murat
Thyroid Stimulating Hormone Receptor
title Thyroid Stimulating Hormone Receptor
title_full Thyroid Stimulating Hormone Receptor
title_fullStr Thyroid Stimulating Hormone Receptor
title_full_unstemmed Thyroid Stimulating Hormone Receptor
title_short Thyroid Stimulating Hormone Receptor
title_sort thyroid stimulating hormone receptor
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283706/
https://www.ncbi.nlm.nih.gov/pubmed/28117293
http://dx.doi.org/10.4274/2017.26.suppl.10
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