Cargando…

The Thyroid Na+/I- Symporter: Molecular Characterization and Genomic Regulation

Iodide (I-) is an essential constituent of the thyroid hormones triiodothyronine (T(3)) and thyroxine (T(4)), and the iodide concentrating mechanism of the thyroid gland is essential for the synthesis of these hormones. In addition, differential uptake of iodine isotopes (radioiodine) is a key modal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alotaibi, Hani, Tuzlakoğlu-Öztürk, Merve, Tazebay, Uygar Halis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Galenos Publishing 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283716/ https://www.ncbi.nlm.nih.gov/pubmed/28117294 http://dx.doi.org/10.4274/2017.26.suppl.11

Ejemplares similares

Intronic elements in the Na+/I- symporter gene (NIS) interact with retinoic acid receptors and mediate initiation of transcription
por: Alotaibi, Hani, et al.
Publicado: (2010)

Identification of novel TUBB1 variants in patients with macrothrombocytopenia
por: ÇALIŞKANER, Zihni Onur, et al.
Publicado: (2021)

Redox Homeostasis in Thyroid Cancer: Implications in Na(+)/I(−) Symporter (NIS) Regulation
por: Cazarin, Juliana, et al.
Publicado: (2022)

Implications of Na(+)/I(-) Symporter Transport to the Plasma Membrane for Thyroid Hormonogenesis and Radioiodide Therapy
por: Martín, Mariano, et al.
Publicado: (2018)

Coiled-Coil Domain Containing Protein 124 Is a Novel Centrosome and Midbody Protein That Interacts with the Ras-Guanine Nucleotide Exchange Factor 1B and Is Involved in Cytokinesis
por: Telkoparan, Pelin, et al.
Publicado: (2013)

Physiological sodium concentrations enhance the iodide affinity of the Na(+)/I(−) symporter
por: Nicola, Juan P., et al.
Publicado: (2014)

Inhibitor binding mode and allosteric regulation of Na(+)-glucose symporters
por: Bisignano, Paola, et al.
Publicado: (2018)

Structure and Mechanism of the Divalent Anion/Na(+) Symporter
por: Lu, Min
Publicado: (2019)

miRNA-106a directly targeting RARB associates with the expression of Na(+)/I(−) symporter in thyroid cancer by regulating MAPK signaling pathway
por: Shen, Chen-Tian, et al.
Publicado: (2016)

Bilateral Shifts in Deuterium Supply Similarly Change Physiology of the Pituitary–Thyroid Axis, but Differentially Influence Na(+)/I(−) Symporter Production
por: Yaglova, Nataliya V., et al.
Publicado: (2023)

Cd81 Interacts with the T Cell Receptor to Suppress Signaling
por: Cevik, Safak Isil, et al.
Publicado: (2012)

Structure-based mechanism for Na(+)/melibiose symport by MelB
por: Ethayathulla, Abdul S., et al.
Publicado: (2014)

An Inverse Agonist of Estrogen-Related Receptor Gamma, GSK5182, Enhances Na(+)/I(−) Symporter Function in Radioiodine-Refractory Papillary Thyroid Cancer Cells
por: Singh, Thoudam Debraj, et al.
Publicado: (2023)

An extremely high dietary iodide supply forestalls severe hypothyroidism in Na(+)/I(−) symporter (NIS) knockout mice
por: Ferrandino, Giuseppe, et al.
Publicado: (2017)

Facile modification of polycaprolactone nanofibers with egg white protein
por: Renkler, Nergis Zeynep, et al.
Publicado: (2021)

Normalisation to Blood Activity Is Required for the Accurate Quantification of Na/I Symporter Ectopic Expression by SPECT/CT in Individual Subjects
por: Richard-Fiardo, Peggy, et al.
Publicado: (2012)

The Ability to Generate Senescent Progeny as a Mechanism Underlying Breast Cancer Cell Heterogeneity
por: Mumcuoglu, Mine, et al.
Publicado: (2010)

Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto's Thyroiditis
por: Popławska-Kita, Anna, et al.
Publicado: (2014)

Mechanism of the Association between Na(+) Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters
por: Stolzenberg, Sebastian, et al.
Publicado: (2015)

Characterization of New Polyol/H(+) Symporters in Debaryomyces hansenii
por: Pereira, Iliana, et al.
Publicado: (2014)

HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells
por: Chai, Wenwen, et al.
Publicado: (2019)

Network analysis reveals essential proteins that regulate sodium-iodide symporter expression in anaplastic thyroid carcinoma
por: Rakhsh-Khorshid, Hassan, et al.
Publicado: (2020)

Structure and function of the divalent anion/Na(+) symporter from Vibrio cholerae and a humanized variant
por: Nie, Rongxin, et al.
Publicado: (2017)

Increased Na/H antiporter and Na/3HCO3 symporter activities in chronic hyperfiltration. A model of cell hypertrophy
Publicado: (1991)

Substrate-bound outward-open structure of a Na(+)-coupled sialic acid symporter reveals a new Na(+) site
por: Wahlgren, Weixiao Y., et al.
Publicado: (2018)

A symporter’s secrets shown
por: Sedwick, Caitlin
Publicado: (2017)

Dimerization of the Sodium/Iodide Symporter
por: Thompson, Rebecca J., et al.
Publicado: (2019)

Insulin-Induced Cardiomyocytes Hypertrophy That Is Prevented by Taurine via β-alanine-Sensitive Na(+)-Taurine Symporter
por: Jazzar, Ashley, et al.
Publicado: (2021)

Resveratrol Inhibits Sodium/Iodide Symporter Gene Expression and Function in Rat Thyroid Cells
por: Giuliani, Cesidio, et al.
Publicado: (2014)

Membrane potential accelerates sugar uptake by stabilizing the outward facing conformation of the Na/glucose symporter vSGLT
por: Khan, Farha, et al.
Publicado: (2023)

Induction of Sodium/Iodide Symporter (NIS) Expression and Radioiodine Uptake in Non-Thyroid Cancer Cells
por: Liu, Zhi, et al.
Publicado: (2012)

Effect of thyroid statuses on sodium/iodide symporter (NIS) gene expression in the extrathyroidal tissues in mice
por: Harun-Or-Rashid, et al.
Publicado: (2010)

Selumetinib Activity in Thyroid Cancer Cells: Modulation of Sodium Iodide Symporter and Associated miRNAs
por: Wächter, Sabine, et al.
Publicado: (2018)

Effect to Therapy of Sodium-Iodine Symporter Expression by Alpha-Ray Therapeutic Agent via Sodium/Iodine Symporter
por: Kaneda-Nakashima, Kazuko, et al.
Publicado: (2022)

Transcription Factor CREB3L1 Regulates the Expression of the Sodium/Iodide Symporter (NIS) in Rat Thyroid Follicular Cells
por: Di Giusto, Pablo, et al.
Publicado: (2022)

Expression of the Na(+)/l(- )symporter (NIS) is markedly decreased or absent in gastric cancer and intestinal metaplastic mucosa of Barrett esophagus
por: Altorjay, Áron, et al.
Publicado: (2007)

Fiber laser-microscope system for femtosecond photodisruption of biological samples
por: Yavaş, Seydi, et al.
Publicado: (2012)

Oncolytic measles viruses encoding interferon β and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy
por: Li, H, et al.
Publicado: (2010)

Effect of Dimerization on the Dynamics of Neurotransmitter:Sodium Symporters
por: Gur, Mert, et al.
Publicado: (2017)

A potassium-proton symport in Neurospora crassa
Publicado: (1986)

Cannot write session to /tmp/vufind_sessions/sess_4dh5npi1a0c6ffb9fa6kqemrh6