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B7-H3 Augments Inflammatory Responses and Exacerbates Brain Damage via Amplifying NF-κB p65 and MAPK p38 Activation during Experimental Pneumococcal Meningitis

The costimulatory protein B7-H3 has been shown to play a contributory role in the development and progression of experimental pneumococcal meningitis by augmentation of the innate immunity-associated inflammatory response via a TLR2-dependent manner. This study aimed to clarify the component(s) of T...

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Detalles Bibliográficos
Autores principales:	Chen, Xuqin, Li, Yan, Blankson, Siobhan, Liu, Min, Huang, Danping, Redmond, H. Paul, Huang, Jing, Wang, Jiang Huai, Wang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283727/ https://www.ncbi.nlm.nih.gov/pubmed/28141831 http://dx.doi.org/10.1371/journal.pone.0171146

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