Progressive APOBEC3B mRNA expression in distant breast cancer metastases

BACKGROUND: APOBEC3B was recently identified as a gain-of-function enzymatic source of mutagenesis, which may offer novel therapeutic options with molecules that specifically target this enzyme. In primary breast cancer, APOBEC3B mRNA is deregulated in a substantial proportion of cases and its expre...

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Detalles Bibliográficos
Autores principales: Sieuwerts, Anieta M., Schrijver, Willemijne A. M. E., Dalm, Simone U., de Weerd, Vanja, Moelans, Cathy B., ter Hoeve, Natalie, van Diest, Paul J., Martens, John W. M., van Deurzen, Carolien H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283735/
https://www.ncbi.nlm.nih.gov/pubmed/28141868
http://dx.doi.org/10.1371/journal.pone.0171343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283735/
https://www.ncbi.nlm.nih.gov/pubmed/28141868
http://dx.doi.org/10.1371/journal.pone.0171343

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