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Inference of Candidate Germline Mutator Loci in Humans from Genome-Wide Haplotype Data
The rate of germline mutation varies widely between species but little is known about the extent of variation in the germline mutation rate between individuals of the same species. Here we demonstrate that an allele that increases the rate of germline mutation can result in a distinctive signature i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283766/ https://www.ncbi.nlm.nih.gov/pubmed/28095480 http://dx.doi.org/10.1371/journal.pgen.1006549 |