Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer

We herein report a rare case of acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer. A 60-year-old man presented with acute and intensive upper abdominal and back pain during chemotherapy with cisplatin and etoposide for lung cancer. Contrast-enhanced computed...

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Detalles Bibliográficos
Autores principales: Koyama, Noriko, Tomoda, Koichi, Matsuda, Masayuki, Fujita, Yukio, Yamamoto, Yoshifumi, Hontsu, Shigeto, Tasaki, Masato, Yoshikawa, Masanori, Kimura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283965/
https://www.ncbi.nlm.nih.gov/pubmed/27980265
Descripción
Sumario:We herein report a rare case of acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer. A 60-year-old man presented with acute and intensive upper abdominal and back pain during chemotherapy with cisplatin and etoposide for lung cancer. Contrast-enhanced computed tomography (CT) revealed bilateral renal and splenic infarctions. After the administration of unfractionated heparin his pain was relieved with a clearance of the infarctions in the CT findings and a recovery of renal dysfunction. Enhanced coagulation by lung cancer and arterial ischemia by chemotherapy may therefore contribute to the development of these infarctions.

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