Cargando…

Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer

We herein report a rare case of acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer. A 60-year-old man presented with acute and intensive upper abdominal and back pain during chemotherapy with cisplatin and etoposide for lung cancer. Contrast-enhanced computed...

Descripción completa

Detalles Bibliográficos
Autores principales: Koyama, Noriko, Tomoda, Koichi, Matsuda, Masayuki, Fujita, Yukio, Yamamoto, Yoshifumi, Hontsu, Shigeto, Tasaki, Masato, Yoshikawa, Masanori, Kimura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283965/
https://www.ncbi.nlm.nih.gov/pubmed/27980265
_version_ 1782503556433051648
author Koyama, Noriko
Tomoda, Koichi
Matsuda, Masayuki
Fujita, Yukio
Yamamoto, Yoshifumi
Hontsu, Shigeto
Tasaki, Masato
Yoshikawa, Masanori
Kimura, Hiroshi
author_facet Koyama, Noriko
Tomoda, Koichi
Matsuda, Masayuki
Fujita, Yukio
Yamamoto, Yoshifumi
Hontsu, Shigeto
Tasaki, Masato
Yoshikawa, Masanori
Kimura, Hiroshi
author_sort Koyama, Noriko
collection PubMed
description We herein report a rare case of acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer. A 60-year-old man presented with acute and intensive upper abdominal and back pain during chemotherapy with cisplatin and etoposide for lung cancer. Contrast-enhanced computed tomography (CT) revealed bilateral renal and splenic infarctions. After the administration of unfractionated heparin his pain was relieved with a clearance of the infarctions in the CT findings and a recovery of renal dysfunction. Enhanced coagulation by lung cancer and arterial ischemia by chemotherapy may therefore contribute to the development of these infarctions.
format Online
Article
Text
id pubmed-5283965
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-52839652017-02-01 Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer Koyama, Noriko Tomoda, Koichi Matsuda, Masayuki Fujita, Yukio Yamamoto, Yoshifumi Hontsu, Shigeto Tasaki, Masato Yoshikawa, Masanori Kimura, Hiroshi Intern Med Case Report We herein report a rare case of acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer. A 60-year-old man presented with acute and intensive upper abdominal and back pain during chemotherapy with cisplatin and etoposide for lung cancer. Contrast-enhanced computed tomography (CT) revealed bilateral renal and splenic infarctions. After the administration of unfractionated heparin his pain was relieved with a clearance of the infarctions in the CT findings and a recovery of renal dysfunction. Enhanced coagulation by lung cancer and arterial ischemia by chemotherapy may therefore contribute to the development of these infarctions. The Japanese Society of Internal Medicine 2016-12-15 /pmc/articles/PMC5283965/ /pubmed/27980265 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Koyama, Noriko
Tomoda, Koichi
Matsuda, Masayuki
Fujita, Yukio
Yamamoto, Yoshifumi
Hontsu, Shigeto
Tasaki, Masato
Yoshikawa, Masanori
Kimura, Hiroshi
Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer
title Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer
title_full Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer
title_fullStr Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer
title_full_unstemmed Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer
title_short Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer
title_sort acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283965/
https://www.ncbi.nlm.nih.gov/pubmed/27980265
work_keys_str_mv AT koyamanoriko acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer
AT tomodakoichi acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer
AT matsudamasayuki acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer
AT fujitayukio acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer
AT yamamotoyoshifumi acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer
AT hontsushigeto acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer
AT tasakimasato acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer
AT yoshikawamasanori acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer
AT kimurahiroshi acutebilateralrenalandsplenicinfarctionsoccurringduringchemotherapyforlungcancer