Chylothorax Associated with Chronic Lymphocytic Leukemia

An 80-year-old man who had suffered from chronic lymphocytic leukemia (CLL) and achieved complete remission was admitted to our hospital due to right pleural effusion. Thoracentesis revealed that the effusion was chyle. Lymphoscintigraphy showed an obstruction of the thoracic duct below the sternum....

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Autores principales: Kohmoto, Osamu, Kawabe, Kazumi, Ono, Hideya, Yanagimoto, Ryuta, Arimoto, Junji, Hatada, Atsutoshi, Suruda, Tadatoshi, Minakata, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283966/
https://www.ncbi.nlm.nih.gov/pubmed/27980266
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author Kohmoto, Osamu
Kawabe, Kazumi
Ono, Hideya
Yanagimoto, Ryuta
Arimoto, Junji
Hatada, Atsutoshi
Suruda, Tadatoshi
Minakata, Yoshiaki
author_facet Kohmoto, Osamu
Kawabe, Kazumi
Ono, Hideya
Yanagimoto, Ryuta
Arimoto, Junji
Hatada, Atsutoshi
Suruda, Tadatoshi
Minakata, Yoshiaki
author_sort Kohmoto, Osamu
collection PubMed
description An 80-year-old man who had suffered from chronic lymphocytic leukemia (CLL) and achieved complete remission was admitted to our hospital due to right pleural effusion. Thoracentesis revealed that the effusion was chyle. Lymphoscintigraphy showed an obstruction of the thoracic duct below the sternum. CD45-gated flow cytometry of the pleural effusion showed elevated numbers of CD5- and CD23-positive lymphocytes and a high serum level of soluble interleukin-2 receptor. These results suggested that the chylothorax was caused by the obstruction of the thoracic duct by the sludging of either abnormal lymphocytes of CLL or transformed malignant lymphoma cells.
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spelling pubmed-52839662017-02-01 Chylothorax Associated with Chronic Lymphocytic Leukemia Kohmoto, Osamu Kawabe, Kazumi Ono, Hideya Yanagimoto, Ryuta Arimoto, Junji Hatada, Atsutoshi Suruda, Tadatoshi Minakata, Yoshiaki Intern Med Case Report An 80-year-old man who had suffered from chronic lymphocytic leukemia (CLL) and achieved complete remission was admitted to our hospital due to right pleural effusion. Thoracentesis revealed that the effusion was chyle. Lymphoscintigraphy showed an obstruction of the thoracic duct below the sternum. CD45-gated flow cytometry of the pleural effusion showed elevated numbers of CD5- and CD23-positive lymphocytes and a high serum level of soluble interleukin-2 receptor. These results suggested that the chylothorax was caused by the obstruction of the thoracic duct by the sludging of either abnormal lymphocytes of CLL or transformed malignant lymphoma cells. The Japanese Society of Internal Medicine 2016-12-15 /pmc/articles/PMC5283966/ /pubmed/27980266 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kohmoto, Osamu
Kawabe, Kazumi
Ono, Hideya
Yanagimoto, Ryuta
Arimoto, Junji
Hatada, Atsutoshi
Suruda, Tadatoshi
Minakata, Yoshiaki
Chylothorax Associated with Chronic Lymphocytic Leukemia
title Chylothorax Associated with Chronic Lymphocytic Leukemia
title_full Chylothorax Associated with Chronic Lymphocytic Leukemia
title_fullStr Chylothorax Associated with Chronic Lymphocytic Leukemia
title_full_unstemmed Chylothorax Associated with Chronic Lymphocytic Leukemia
title_short Chylothorax Associated with Chronic Lymphocytic Leukemia
title_sort chylothorax associated with chronic lymphocytic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283966/
https://www.ncbi.nlm.nih.gov/pubmed/27980266
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