The cyclin-dependent kinase inhibitor AT7519 accelerates neutrophil apoptosis in sepsis-related acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a neutrophil-dominant disorder with no effective pharmacological therapies. While the cyclin-dependent kinase inhibitor AT7519 induces neutrophil apoptosis to promote inflammation resolution in preclinical models of lung inflammation, its potential effic...

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Detalles Bibliográficos
Autores principales: Dorward, David A, Felton, Jennifer M, Robb, Calum T, Craven, Thomas, Kipari, Tiina, Walsh, Timothy S, Haslett, Christopher, Kefala, Kallirroi, Rossi, Adriano G, Lucas, Christopher D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5284332/
https://www.ncbi.nlm.nih.gov/pubmed/27965411
http://dx.doi.org/10.1136/thoraxjnl-2016-209229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5284332/
https://www.ncbi.nlm.nih.gov/pubmed/27965411
http://dx.doi.org/10.1136/thoraxjnl-2016-209229

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