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The Deubiquitinating Enzyme Cylindromatosis Dampens CD8(+) T Cell Responses and Is a Critical Factor for Experimental Cerebral Malaria and Blood–Brain Barrier Damage
Cerebral malaria is a severe complication of human malaria and may lead to death of Plasmodium falciparum-infected individuals. Cerebral malaria is associated with sequestration of parasitized red blood cells within the cerebral microvasculature resulting in damage of the blood–brain barrier and bra...
Autores principales: | Schmid, Ursula, Stenzel, Werner, Koschel, Josephin, Raptaki, Maria, Wang, Xu, Naumann, Michael, Matuschewski, Kai, Schlüter, Dirk, Nishanth, Gopala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285367/ https://www.ncbi.nlm.nih.gov/pubmed/28203236 http://dx.doi.org/10.3389/fimmu.2017.00027 |
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