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Insulin-Like Growth Factor 1: At the Crossroads of Brain Development and Aging
Insulin-like growth factor 1 (IGF1) is a polypeptide hormone structurally similar to insulin. It is central to the somatotropic axis, acting downstream of growth hormone (GH). It activates both the mitogen-activated protein (MAP) kinase and PI3K signaling pathways, acting in almost every tissue in t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285390/ https://www.ncbi.nlm.nih.gov/pubmed/28203146 http://dx.doi.org/10.3389/fncel.2017.00014 |