Cargando…

Insulin-Like Growth Factor 1: At the Crossroads of Brain Development and Aging

Insulin-like growth factor 1 (IGF1) is a polypeptide hormone structurally similar to insulin. It is central to the somatotropic axis, acting downstream of growth hormone (GH). It activates both the mitogen-activated protein (MAP) kinase and PI3K signaling pathways, acting in almost every tissue in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wrigley, Sarah, Arafa, Donia, Tropea, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285390/ https://www.ncbi.nlm.nih.gov/pubmed/28203146 http://dx.doi.org/10.3389/fncel.2017.00014

Ejemplares similares

Insulin-Like Growth Factor 1 and Related Compounds in the Treatment of Childhood-Onset Neurodevelopmental Disorders
por: Vahdatpour, Cyrus, et al.
Publicado: (2016)

Clinical development of insulin-like growth factor receptor—1 (IGF-1R) inhibitors: At the crossroad?
por: Gombos, Andrea, et al.
Publicado: (2012)

Insulin-like growth factor-1 in CNS and cerebrovascular aging
por: Sonntag, William E., et al.
Publicado: (2013)

Insulin-Like Growth Factor-1 Is Neuroprotective in Aged Rats With Ischemic Stroke
por: Serhan, Ahmad, et al.
Publicado: (2019)

Insulin-Like Growth Factor-1 and Neuroinflammation
por: Labandeira-Garcia, Jose L., et al.
Publicado: (2017)

The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss
por: Rodríguez-de la Rosa, Lourdes, et al.
Publicado: (2017)

Dose-Dependent Effects of Insulin-Like Growth Factor 1 in the Aged Olfactory Epithelium
por: Ueha, Rumi, et al.
Publicado: (2018)

DMT1 Expression and Iron Levels at the Crossroads Between Aging and Neurodegeneration
por: Ingrassia, Rosaria, et al.
Publicado: (2019)

Cell cycle control by the insulin-like growth factor signal: at the crossroad between cell growth and mitotic regulation
por: Scalia, Pierluigi, et al.
Publicado: (2022)

The Neuromuscular Junction: Aging at the Crossroad between Nerves and Muscle
por: Gonzalez-Freire, Marta, et al.
Publicado: (2014)

Reduced Insulin-Like Growth Factor-I Effects in the Basal Forebrain of Aging Mouse
por: Zegarra-Valdivia, Jonathan A., et al.
Publicado: (2021)

Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity
por: Chen, Wei, et al.
Publicado: (2019)

The Role of Insulin-Like Growth Factor-I in the Physiopathology of Hearing
por: Murillo-Cuesta, Silvia, et al.
Publicado: (2011)

Insulin-Like Growth Factors in Development, Cancers and Aging
por: Werner, Haim
Publicado: (2020)

The Aging Brain: Crossroad of Normal Aging and Dementia
por: Tian, Qu, et al.
Publicado: (2020)

Protocadherins at the Crossroad of Signaling Pathways
por: Pancho, Anna, et al.
Publicado: (2020)

Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP(swe)/PS1(ΔE9) Transgenic Mice
por: Myhre, Christa Løth, et al.
Publicado: (2019)

An Insulin-Like Growth Factor in Rhodnius prolixus Is Involved in Post-feeding Nutrient Balance and Growth
por: Defferrari, Marina S., et al.
Publicado: (2016)

Editorial: Biology of Brain Disorders
por: Tropea, Daniela, et al.
Publicado: (2017)

Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs
por: Christiansen, Line I., et al.
Publicado: (2023)

A Comparative Study of Age-Related Hearing Loss in Wild Type and Insulin-Like Growth Factor I Deficient Mice
por: Riquelme, Raquel, et al.
Publicado: (2010)

Rac1 at the crossroad of actin dynamics and neuroinflammation in Amyotrophic Lateral Sclerosis
por: D’Ambrosi, Nadia, et al.
Publicado: (2014)

Local autocrine plasticity signaling in single dendritic spines by insulin-like growth factors
por: Tu, Xun, et al.
Publicado: (2023)

Insulin-Like Growth Factor-1 Differentially Modulates Glutamate-Induced Toxicity and Stress in Cells of the Neurogliovascular Unit
por: Hayes, Cellas A., et al.
Publicado: (2021)

Extrinsic and intrinsic regulation of axon regeneration at a crossroads
por: Kaplan, Andrew, et al.
Publicado: (2015)

Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons
por: Giuffrida, Maria L., et al.
Publicado: (2015)

Insulin-Like Growth Factor 1 on the Maintenance of Ribbon Synapses in Mouse Cochlear Explant Cultures
por: Gao, Li, et al.
Publicado: (2020)

Deciphering Brain Insulin Receptor and Insulin‐Like Growth Factor 1 Receptor Signalling
por: Kleinridders, A.
Publicado: (2016)

Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss
por: Partearroyo, Teresa, et al.
Publicado: (2017)

Insulin-Like Growth Factor-1 Down-Regulates the Phosphorylation of FXYD1 and Rescues Behavioral Deficits in a Mouse Model of Rett Syndrome
por: Yuan, Zhe-Feng, et al.
Publicado: (2020)

The Overexpression of Insulin-Like Growth Factor-1 and Neurotrophin-3 Promote Functional Recovery and Alleviate Spasticity After Spinal Cord Injury
por: Talifu, Zuliyaer, et al.
Publicado: (2022)

Revisiting the Role of Insulin-Like Growth Factor-I Receptor Stimulating Activity and the Apolipoprotein E in Alzheimer’s Disease
por: Galle, Sara A., et al.
Publicado: (2019)

Insulin-Like Growth Factor Receptor Signaling is Necessary for Epidermal Growth Factor Mediated Proliferation of SVZ Neural Precursors in vitro Following Neonatal Hypoxia–Ischemia
por: Alagappan, Dhivyaa, et al.
Publicado: (2014)

Lipids at the Crossroad of α-Synuclein Function and Dysfunction: Biological and Pathological Implications
por: Alza, Natalia P., et al.
Publicado: (2019)

Computational Models of Anterior Cingulate Cortex: At the Crossroads between Prediction and Effort
por: Vassena, Eliana, et al.
Publicado: (2017)

Editorial: Hereditary Spastic Paraplegias: At the Crossroads of Molecular Pathways and Clinical Options
por: Martinuzzi, Andrea, et al.
Publicado: (2021)

Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging
por: Miller, Lauren R., et al.
Publicado: (2022)

Prospero-related homeobox 1 (Prox1) at the crossroads of diverse pathways during adult neural fate specification
por: Stergiopoulos, Athanasios, et al.
Publicado: (2015)

Role of Insulin-like Growth Factor, Insulin-like Growth Factor Receptors, and Insulin-like Growth Factor-binding Proteins in Ovarian Cancer
por: Amutha, Periyasamy, et al.
Publicado: (2017)

Is insulin-like growth factor-1 involved in Parkinson’s disease development?
por: Castilla-Cortázar, Inma, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tidb1mlhcb60v9s7ut5i962ujn