Cargando…

Comparative study of idursulfase beta and idursulfase in vitro and in vivo

Hunter syndrome is an X-linked lysosomal storage disease caused by a deficiency in the enzyme iduronate-2-sulfatase (IDS), leading to the accumulation of glycosaminoglycans (GAGs). Two recombinant enzymes, idursulfase and idursulfase beta are currently available for enzyme replacement therapy for Hu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Chihwa, Seo, Jinwook, Chung, Yokyung, Ji, Hyi-Jeong, Lee, Jaehyeon, Sohn, Jongmun, Lee, Byoungju, Jo, Eui-cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285491/
https://www.ncbi.nlm.nih.gov/pubmed/27829684
http://dx.doi.org/10.1038/jhg.2016.133