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Differential Binding of Mitochondrial Transcripts by MRB8170 and MRB4160 Regulates Distinct Editing Fates of Mitochondrial mRNA in Trypanosomes
A dozen mRNAs are edited by multiple insertions and/or deletions of uridine residues in the mitochondrion of Trypanosoma brucei. Several protein complexes have been implicated in performing this type of RNA editing, including the mitochondrial RNA-binding complex 1 (MRB1). Two paralogous novel RNA-b...
Autores principales: | Dixit, Sameer, Müller-McNicoll, Michaela, David, Vojtěch, Zarnack, Kathi, Ule, Jernej, Hashimi, Hassan, Lukeš, Julius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285507/ https://www.ncbi.nlm.nih.gov/pubmed/28143982 http://dx.doi.org/10.1128/mBio.02288-16 |
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