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Doxycycline Induces Mitophagy and Suppresses Production of Interferon-β in IPEC-J2 Cells

Previous reports have demonstrated that the second-generation tetracycline derivative doxycycline (DOX) interrupts mitochondrial proteostasis and physiology, inhibits proliferation of many cell types, and induces apoptosis. However, the effects of DOX, which is widely used in porcine husbandry by fe...

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Detalles Bibliográficos
Autores principales: Xing, Yang, Liqi, Zhu, Jian, Lin, Qinghua, Yu, Qian, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285722/
https://www.ncbi.nlm.nih.gov/pubmed/28203548
http://dx.doi.org/10.3389/fcimb.2017.00021