Changing POU dimerization preferences converts Oct6 into a pluripotency inducer

The transcription factor Oct4 is a core component of molecular cocktails inducing pluripotent stem cells (iPSCs), while other members of the POU family cannot replace Oct4 with comparable efficiency. Rather, group III POU factors such as Oct6 induce neural lineages. Here, we sought to identify molec...

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Detalles Bibliográficos
Autores principales: Jerabek, Stepan, Ng, Calista KL, Wu, Guangming, Arauzo‐Bravo, Marcos J, Kim, Kee‐Pyo, Esch, Daniel, Malik, Vikas, Chen, Yanpu, Velychko, Sergiy, MacCarthy, Caitlin M, Yang, Xiaoxiao, Cojocaru, Vlad, Schöler, Hans R, Jauch, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286379/
https://www.ncbi.nlm.nih.gov/pubmed/28007765
http://dx.doi.org/10.15252/embr.201642958

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