Cargando…

miR-34a inhibits pancreatic cancer progression through Snail1-mediated epithelial–mesenchymal transition and the Notch signaling pathway

Epithelial–mesenchymal transition (EMT) and Notch signaling are important for the growth and invasion of pancreatic cancer, which is a leading cause of cancer-related deaths worldwide. miR-34a has been shown to play pivotal roles in the progression of several types of cancer. However, little is know...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Yan, Tang, Yong, Cheng, Ying-sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286431/ https://www.ncbi.nlm.nih.gov/pubmed/28145431 http://dx.doi.org/10.1038/srep38232

Ejemplares similares

MiR-363 inhibits cisplatin chemoresistance of epithelial ovarian cancer by regulating snail-induced epithelial-mesenchymal transition
por: Cao, Lanqin, et al.
Publicado: (2018)

Exosomal miR-34b inhibits proliferation and the epithelial-mesenchymal transition by targeting Notch2 in ovarian cancer
por: Lu, Shenglian, et al.
Publicado: (2020)

Regulations of miR-183-5p and Snail-Mediated Shikonin-Reduced Epithelial-Mesenchymal Transition in Cervical Cancer Cells
por: Tang, Qing, et al.
Publicado: (2020)

The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer
por: Yu, Wei-Wei, et al.
Publicado: (2017)

miR-34c attenuates epithelial-mesenchymal transition and kidney fibrosis with ureteral obstruction
por: Morizane, Ryuji, et al.
Publicado: (2014)

miR-381-3p suppresses breast cancer progression by inhibition of epithelial–mesenchymal transition
por: Yu, Yong-Zheng, et al.
Publicado: (2021)

Long Noncoding RNA NEAT1 Regulates TGF-β2-Induced Epithelial-Mesenchymal Transition of Lens Epithelial Cells through the miR-34a/Snail1 and miR-204/Zeb1 Pathways
por: Dong, Ning
Publicado: (2020)

miR-486-5p suppresses prostate cancer metastasis by targeting Snail and regulating epithelial–mesenchymal transition
por: Zhang, Xiaoguang, et al.
Publicado: (2016)

MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell
por: Lu, Yuhua, et al.
Publicado: (2014)

miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer
por: Hiramoto, Hidekazu, et al.
Publicado: (2017)

MiR-221/222 promote epithelial-mesenchymal transition by targeting Notch3 in breast cancer cell lines
por: Liang, Yuan-Ke, et al.
Publicado: (2018)

WISP-1 Promotes Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma Cells via the miR-153-3p/Snail Axis
por: Chang, An-Chen, et al.
Publicado: (2019)

MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop
por: Xu, Mingjie, et al.
Publicado: (2018)

LncRNA MALAT1 Regulates miR-144-3p to Facilitate Epithelial-Mesenchymal Transition of Lens Epithelial Cells via the ROS/NRF2/Notch1/Snail Pathway
por: Ye, Wei, et al.
Publicado: (2020)

Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma
por: Chen, Yan, et al.
Publicado: (2019)

Targeting the Notch1 oncogene by miR-139-5p inhibits glioma metastasis and epithelial-mesenchymal transition (EMT)
por: Li, Jianlong, et al.
Publicado: (2018)

MET/SMAD3/SNAIL circuit mediated by miR-323a-3p is involved in regulating epithelial–mesenchymal transition progression in bladder cancer
por: Li, Jiangfeng, et al.
Publicado: (2017)

Correction to: Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma
por: Chen, Yan, et al.
Publicado: (2021)

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition
por: Kim, Nam Hee, et al.
Publicado: (2011)

Aberrant expression of Notch1/numb/snail signaling, an epithelial mesenchymal transition related pathway, in adenomyosis
por: Qi, Shasha, et al.
Publicado: (2015)

Curcumin rescues breast cells from epithelial-mesenchymal transition and invasion induced by anti-miR-34a
por: Gallardo, Marcela, et al.
Publicado: (2019)

LncRNA‐ATB regulates epithelial‐mesenchymal transition progression in pulmonary fibrosis via sponging miR‐29b‐2‐5p and miR‐34c‐3p
por: Xu, Qi, et al.
Publicado: (2021)

MiR-940 inhibits TGF-β-induced epithelial-mesenchymal transition and cell invasion by targeting Snail in non-small cell lung cancer
por: Jiang, Kanqiu, et al.
Publicado: (2019)

miR-126 suppresses epithelial-to-mesenchymal transition and metastasis by targeting PI3K/AKT/Snail signaling of lung cancer cells
por: Jia, Zhijun, et al.
Publicado: (2018)

Snail1-expressing cancer-associated fibroblasts induce lung cancer cell epithelial-mesenchymal transition through miR-33b
por: You, Jia, et al.
Publicado: (2017)

The effect and mechanism of miR-30e-5p targeting SNAI1 to regulate epithelial-mesenchymal transition on pancreatic cancer
por: Liang, Ziyu, et al.
Publicado: (2022)

A Presenilin/Notch1 pathway regulated by miR-375, miR-30a, and miR-34a mediates glucotoxicity induced-pancreatic beta cell apoptosis
por: Li, Yating, et al.
Publicado: (2016)

MiR-1301-3p Inhibits Epithelial-Mesenchymal Transition via Targeting RhoA in Pancreatic Cancer
por: Zhang, Xinxue, et al.
Publicado: (2022)

Correction: MiR-940 inhibits TGF-β-induced epithelial-mesenchymal transition and cell invasion by targeting Snail in non-small cell lung cancer
por: Jiang, Kanqiu, et al.
Publicado: (2020)

Transcriptional inhibition of miR-486-3p by BCL6 upregulates Snail and induces epithelial–mesenchymal transition during radiation-induced pulmonary fibrosis
por: Yan, Ziyan, et al.
Publicado: (2022)

miR-665 Suppresses the Epithelial–Mesenchymal Transition and Progression of Gastric Cancer by Targeting CRIM1
por: Wu, Kun-Zhe, et al.
Publicado: (2020)

MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma
por: Vychytilova-Faltejskova, Petra, et al.
Publicado: (2015)

MiR-137 and miR-34a directly target Snail and inhibit EMT, invasion and sphere-forming ability of ovarian cancer cells
por: Dong, Peixin, et al.
Publicado: (2016)

Down‐regulation of microRNAs of the miR‐200 family and up‐regulation of Snail and Slug in inflammatory bowel diseases — hallmark of epithelial−mesenchymal transition
por: Zidar, Nina, et al.
Publicado: (2016)

Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice
por: Yang, Guannan, et al.
Publicado: (2017)

Down-regulation of miR-223 reverses epithelial-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
por: Ma, Jia, et al.
Publicado: (2015)

miR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transition
por: Wang, Lin, et al.
Publicado: (2015)

Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition
por: Haraguchi, Takeshi, et al.
Publicado: (2016)

MTF2 Induces Epithelial-Mesenchymal Transition and Progression of Hepatocellular Carcinoma by Transcriptionally Activating Snail
por: Wu, Tian-Tian, et al.
Publicado: (2019)

Platelet microparticle-mediated transfer of miR-939 to epithelial ovarian cancer cells promotes epithelial to mesenchymal transition
por: Tang, Meiling, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_6d515nvob2f0jkpl2489l3kgds