Transplanted miR-219-overexpressing oligodendrocyte precursor cells promoted remyelination and improved functional recovery in a chronic demyelinated model

Oligodendrocyte precursor cells (OPCs) have the ability to repair demyelinated lesions by maturing into myelin-producing oligodendrocytes. Recent evidence suggests that miR-219 helps regulate the differentiation of OPCs into oligodendrocytes. We performed oligodendrocyte differentiation studies usin...

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Detalles Bibliográficos
Autores principales: Fan, Hong-Bin, Chen, Li-Xia, Qu, Xue-Bin, Ren, Chuan-Lu, Wu, Xiu-Xiang, Dong, Fu-Xing, Zhang, Bao-Le, Gao, Dian-Shuai, Yao, Rui-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286453/
https://www.ncbi.nlm.nih.gov/pubmed/28145507
http://dx.doi.org/10.1038/srep41407

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