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Effect of R119G Mutation on Human P5CR1 Dynamic Property and Enzymatic Activity

Pyrroline-5-carboxylate reductase (P5CR1) is a universal housekeeping enzyme that catalyzes the reduction of Δ1-pyrroline-5-carboxylate (P5C) to proline with concomitant oxidation of NAD(P)H to NAD(P)(+). The enzymatic cycle between P5C and proline is important for function in amino acid metabolism,...

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Detalles Bibliográficos
Autores principales:	Li, Linhua, Ye, Yujia, Sang, Peng, Yin, Yirui, Hu, Wei, Wang, Jing, Zhang, Chao, Li, Deyun, Wan, Wen, Li, Rui, Li, Longjun, Ma, Linling, Xie, Yuehui, Meng, Zhaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286483/ https://www.ncbi.nlm.nih.gov/pubmed/28194412 http://dx.doi.org/10.1155/2017/4184106

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