Disturbed Matrix Metalloproteinase Pathway in Both Age-Related Macular Degeneration and Alzheimer's Disease

Purpose. Abnormal protein deposits including β-amyloid, found in ageing Bruch's membrane and brain, are susceptible to degradation by matrix metalloproteinases (MMPs). In ageing Bruch's membrane, these MMPs become less effective due to polymerisation and aggregation reactions (constituting...

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Detalles Bibliográficos
Autores principales: Hussain, Ali Aijaz, Lee, Yunhee, Zhang, Jin-Jun, Francis, Paul T., Marshall, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286539/
https://www.ncbi.nlm.nih.gov/pubmed/28197357
http://dx.doi.org/10.1155/2017/4810232

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