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Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872

The article provides an overview of the genomic features of Lactobacillus fermentum strain 3872. The genomic sequence reported here is one of three L. fermentum genome sequences completed to date. Comparative genomic analysis allowed the identification of genes that may be contributing to enhanced p...

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Detalles Bibliográficos
Autores principales: Lehri, Burhan, Seddon, Alan M., Karlyshev, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286655/
https://www.ncbi.nlm.nih.gov/pubmed/28163828
http://dx.doi.org/10.1186/s40793-017-0228-4
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author Lehri, Burhan
Seddon, Alan M.
Karlyshev, Andrey V.
author_facet Lehri, Burhan
Seddon, Alan M.
Karlyshev, Andrey V.
author_sort Lehri, Burhan
collection PubMed
description The article provides an overview of the genomic features of Lactobacillus fermentum strain 3872. The genomic sequence reported here is one of three L. fermentum genome sequences completed to date. Comparative genomic analysis allowed the identification of genes that may be contributing to enhanced probiotic properties of this strain. In particular, the genes encoding putative mucus binding proteins, collagen-binding proteins, class III bacteriocin, as well as exopolysaccharide and prophage-related genes were identified. Genes related to bacterial aggregation and survival under harsh conditions in the gastrointestinal tract, along with the genes required for vitamin production were also found. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40793-017-0228-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-52866552017-02-03 Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872 Lehri, Burhan Seddon, Alan M. Karlyshev, Andrey V. Stand Genomic Sci Extended Genome Report The article provides an overview of the genomic features of Lactobacillus fermentum strain 3872. The genomic sequence reported here is one of three L. fermentum genome sequences completed to date. Comparative genomic analysis allowed the identification of genes that may be contributing to enhanced probiotic properties of this strain. In particular, the genes encoding putative mucus binding proteins, collagen-binding proteins, class III bacteriocin, as well as exopolysaccharide and prophage-related genes were identified. Genes related to bacterial aggregation and survival under harsh conditions in the gastrointestinal tract, along with the genes required for vitamin production were also found. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40793-017-0228-4) contains supplementary material, which is available to authorized users. BioMed Central 2017-02-01 /pmc/articles/PMC5286655/ /pubmed/28163828 http://dx.doi.org/10.1186/s40793-017-0228-4 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Extended Genome Report
Lehri, Burhan
Seddon, Alan M.
Karlyshev, Andrey V.
Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872
title Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872
title_full Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872
title_fullStr Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872
title_full_unstemmed Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872
title_short Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872
title_sort potential probiotic-associated traits revealed from completed high quality genome sequence of lactobacillus fermentum 3872
topic Extended Genome Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286655/
https://www.ncbi.nlm.nih.gov/pubmed/28163828
http://dx.doi.org/10.1186/s40793-017-0228-4
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