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Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872
The article provides an overview of the genomic features of Lactobacillus fermentum strain 3872. The genomic sequence reported here is one of three L. fermentum genome sequences completed to date. Comparative genomic analysis allowed the identification of genes that may be contributing to enhanced p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286655/ https://www.ncbi.nlm.nih.gov/pubmed/28163828 http://dx.doi.org/10.1186/s40793-017-0228-4 |
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author | Lehri, Burhan Seddon, Alan M. Karlyshev, Andrey V. |
author_facet | Lehri, Burhan Seddon, Alan M. Karlyshev, Andrey V. |
author_sort | Lehri, Burhan |
collection | PubMed |
description | The article provides an overview of the genomic features of Lactobacillus fermentum strain 3872. The genomic sequence reported here is one of three L. fermentum genome sequences completed to date. Comparative genomic analysis allowed the identification of genes that may be contributing to enhanced probiotic properties of this strain. In particular, the genes encoding putative mucus binding proteins, collagen-binding proteins, class III bacteriocin, as well as exopolysaccharide and prophage-related genes were identified. Genes related to bacterial aggregation and survival under harsh conditions in the gastrointestinal tract, along with the genes required for vitamin production were also found. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40793-017-0228-4) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5286655 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-52866552017-02-03 Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872 Lehri, Burhan Seddon, Alan M. Karlyshev, Andrey V. Stand Genomic Sci Extended Genome Report The article provides an overview of the genomic features of Lactobacillus fermentum strain 3872. The genomic sequence reported here is one of three L. fermentum genome sequences completed to date. Comparative genomic analysis allowed the identification of genes that may be contributing to enhanced probiotic properties of this strain. In particular, the genes encoding putative mucus binding proteins, collagen-binding proteins, class III bacteriocin, as well as exopolysaccharide and prophage-related genes were identified. Genes related to bacterial aggregation and survival under harsh conditions in the gastrointestinal tract, along with the genes required for vitamin production were also found. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40793-017-0228-4) contains supplementary material, which is available to authorized users. BioMed Central 2017-02-01 /pmc/articles/PMC5286655/ /pubmed/28163828 http://dx.doi.org/10.1186/s40793-017-0228-4 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Extended Genome Report Lehri, Burhan Seddon, Alan M. Karlyshev, Andrey V. Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872 |
title | Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872 |
title_full | Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872 |
title_fullStr | Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872 |
title_full_unstemmed | Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872 |
title_short | Potential probiotic-associated traits revealed from completed high quality genome sequence of Lactobacillus fermentum 3872 |
title_sort | potential probiotic-associated traits revealed from completed high quality genome sequence of lactobacillus fermentum 3872 |
topic | Extended Genome Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286655/ https://www.ncbi.nlm.nih.gov/pubmed/28163828 http://dx.doi.org/10.1186/s40793-017-0228-4 |
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