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Sex in the brain: hormones and sex differences
Contrary to popular belief, sex hormones act throughout the entire brain of both males and females via both genomic and nongenomic receptors. Many neural and behavioral functions are affected by estrogens, including mood, cognitive function, blood pressure regulation, motor coordination, pain, and o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Les Laboratoires Servier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286723/ https://www.ncbi.nlm.nih.gov/pubmed/28179809 |
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author | Marrocco, Jordan McEwen, Bruce S. |
author_facet | Marrocco, Jordan McEwen, Bruce S. |
author_sort | Marrocco, Jordan |
collection | PubMed |
description | Contrary to popular belief, sex hormones act throughout the entire brain of both males and females via both genomic and nongenomic receptors. Many neural and behavioral functions are affected by estrogens, including mood, cognitive function, blood pressure regulation, motor coordination, pain, and opioid sensitivity. Subtle sex differences exist for many of these functions that are developmentally programmed by hormones and by not yet precisely defined genetic factors, including the mitochondrial genome. These sex differences, and responses to sex hormones in brain regions and upon functions not previously regarded as subject to such differences, indicate that we are entering a new era in our ability to understand and appreciate the diversity of gender-related behaviors and brain functions. |
format | Online Article Text |
id | pubmed-5286723 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Les Laboratoires Servier |
record_format | MEDLINE/PubMed |
spelling | pubmed-52867232017-02-08 Sex in the brain: hormones and sex differences Marrocco, Jordan McEwen, Bruce S. Dialogues Clin Neurosci Basic Research Contrary to popular belief, sex hormones act throughout the entire brain of both males and females via both genomic and nongenomic receptors. Many neural and behavioral functions are affected by estrogens, including mood, cognitive function, blood pressure regulation, motor coordination, pain, and opioid sensitivity. Subtle sex differences exist for many of these functions that are developmentally programmed by hormones and by not yet precisely defined genetic factors, including the mitochondrial genome. These sex differences, and responses to sex hormones in brain regions and upon functions not previously regarded as subject to such differences, indicate that we are entering a new era in our ability to understand and appreciate the diversity of gender-related behaviors and brain functions. Les Laboratoires Servier 2016-12 /pmc/articles/PMC5286723/ /pubmed/28179809 Text en Copyright: © 2016 Institut la Conference Hippocrate - Servier Research Group http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Basic Research Marrocco, Jordan McEwen, Bruce S. Sex in the brain: hormones and sex differences |
title | Sex in the brain: hormones and sex differences |
title_full | Sex in the brain: hormones and sex differences |
title_fullStr | Sex in the brain: hormones and sex differences |
title_full_unstemmed | Sex in the brain: hormones and sex differences |
title_short | Sex in the brain: hormones and sex differences |
title_sort | sex in the brain: hormones and sex differences |
topic | Basic Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286723/ https://www.ncbi.nlm.nih.gov/pubmed/28179809 |
work_keys_str_mv | AT marroccojordan sexinthebrainhormonesandsexdifferences AT mcewenbruces sexinthebrainhormonesandsexdifferences |