Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin

BACKGROUND: Translationally controlled tumour protein TCTP is an anti-apoptotic protein frequently overexpressed in cancers, where high levels are often associated with poor patient outcome. TCTP may be involved in protecting cancer cells against the cytotoxic action of anti-cancer drugs. Here we st...

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Detalles Bibliográficos
Autores principales: Bommer, Ulrich-Axel, Vine, Kara L., Puri, Prianka, Engel, Martin, Belfiore, Lisa, Fildes, Karen, Batterham, Marijka, Lochhead, Alistair, Aghmesheh, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286767/
https://www.ncbi.nlm.nih.gov/pubmed/28143584
http://dx.doi.org/10.1186/s12964-017-0164-3

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