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Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells

BACKGROUND: The initiation and progression of malignant tumors is driven by distinct subsets of tumor-initiating or cancer stem-like cells (CSCs) which develop therapy/apoptosis resistance and self-renewal capacity. In order to be able to eradicate these CSCs with novel classes of anti-cancer therap...

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Detalles Bibliográficos
Autores principales:	Melzer, Catharina, von der Ohe, Juliane, Lehnert, Hendrik, Ungefroren, Hendrik, Hass, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286787/ https://www.ncbi.nlm.nih.gov/pubmed/28148265 http://dx.doi.org/10.1186/s12943-017-0595-x

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