The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells

BACKGROUND: Advanced urothelial carcinomas represent a considerable clinical challenge as they are difficult to treat. Platinum-based combination regimens obtain response rates ranging from 40 to 70% in first-line therapy of advanced urothelial carcinoma. In the majority of cases, however, the durat...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Madanchi, Ramin, Hauschild, Jessica, Otte, Katharina, Alsdorf, Winfried H., Schumacher, Udo, Kalinin, Vladimir I., Silchenko, Alexandra S., Avilov, Sergey A., Honecker, Friedemann, Stonik, Valentin A., Bokemeyer, Carsten, von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286817/
https://www.ncbi.nlm.nih.gov/pubmed/28143426
http://dx.doi.org/10.1186/s12885-017-3085-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286817/
https://www.ncbi.nlm.nih.gov/pubmed/28143426
http://dx.doi.org/10.1186/s12885-017-3085-z

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