Relevance of epithelial-to-pericyte transition in cancer

The relevance of epithelial-to-mesenchymal transition (EMT) in cancer is still under debate. Recently, we reported that EMT bestows key pericyte properties on cancer cells and may thus represent epithelial-to-pericyte transition (EPT). Carcinoma cells undergo EPT to stabilize blood vessels and fuel...

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Detalles Bibliográficos
Autores principales: Shenoy, Anitha K., Lu, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286925/
https://www.ncbi.nlm.nih.gov/pubmed/28197535
http://dx.doi.org/10.1080/23723556.2016.1260672
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author Shenoy, Anitha K.
Lu, Jianrong
author_facet Shenoy, Anitha K.
Lu, Jianrong
author_sort Shenoy, Anitha K.
collection PubMed
description The relevance of epithelial-to-mesenchymal transition (EMT) in cancer is still under debate. Recently, we reported that EMT bestows key pericyte properties on cancer cells and may thus represent epithelial-to-pericyte transition (EPT). Carcinoma cells undergo EPT to stabilize blood vessels and fuel primary tumor growth. Association of EPT cancer cells with vascular niches may also promote resistance to therapy.
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spelling pubmed-52869252017-11-22 Relevance of epithelial-to-pericyte transition in cancer Shenoy, Anitha K. Lu, Jianrong Mol Cell Oncol Author's View The relevance of epithelial-to-mesenchymal transition (EMT) in cancer is still under debate. Recently, we reported that EMT bestows key pericyte properties on cancer cells and may thus represent epithelial-to-pericyte transition (EPT). Carcinoma cells undergo EPT to stabilize blood vessels and fuel primary tumor growth. Association of EPT cancer cells with vascular niches may also promote resistance to therapy. Taylor & Francis 2016-11-22 /pmc/articles/PMC5286925/ /pubmed/28197535 http://dx.doi.org/10.1080/23723556.2016.1260672 Text en © 2017 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Author's View
Shenoy, Anitha K.
Lu, Jianrong
Relevance of epithelial-to-pericyte transition in cancer
title Relevance of epithelial-to-pericyte transition in cancer
title_full Relevance of epithelial-to-pericyte transition in cancer
title_fullStr Relevance of epithelial-to-pericyte transition in cancer
title_full_unstemmed Relevance of epithelial-to-pericyte transition in cancer
title_short Relevance of epithelial-to-pericyte transition in cancer
title_sort relevance of epithelial-to-pericyte transition in cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286925/
https://www.ncbi.nlm.nih.gov/pubmed/28197535
http://dx.doi.org/10.1080/23723556.2016.1260672
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AT lujianrong relevanceofepithelialtopericytetransitionincancer

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