Description of the Thermotropic Behavior Of Membrane Bilayers In Terms of Raman Spectral Parameters: A Two-State Model

An analytical expression is developed for describing the thermotropic behavior of membrane bilayers as studied by Raman spectroscopy. The expression is derived from a two-state model of the main gel to liquid crystalline phase transition in lipid bilayers. Experimental data for a variety of diacylph...

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Detalles Bibliográficos
Autores principales: Kirchhoff, William H., Levin, Ira W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: [Gaithersburg, MD] : U.S. Dept. of Commerce, National Institute of Standards and Technology 1987
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286997/
http://dx.doi.org/10.6028/jres.092.012
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author Kirchhoff, William H.
Levin, Ira W.
author_facet Kirchhoff, William H.
Levin, Ira W.
author_sort Kirchhoff, William H.
collection PubMed
description An analytical expression is developed for describing the thermotropic behavior of membrane bilayers as studied by Raman spectroscopy. The expression is derived from a two-state model of the main gel to liquid crystalline phase transition in lipid bilayers. Experimental data for a variety of diacylphosphatidylcholines and their derivatives have been fit by least squares to the two-state expression to within currently achievable measurement error. Numerical techniques have been developed for placing bounds on the parameters of the two-state model in situations of sparse data in the phase transition region. By fitting the model to the measured spectroscopic data, estimates of the extent of cooperativity in the phase transition can be obtained in a systematic manner.
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spelling pubmed-52869972021-08-02 Description of the Thermotropic Behavior Of Membrane Bilayers In Terms of Raman Spectral Parameters: A Two-State Model Kirchhoff, William H. Levin, Ira W. J Res Natl Bur Stand (1977) Article An analytical expression is developed for describing the thermotropic behavior of membrane bilayers as studied by Raman spectroscopy. The expression is derived from a two-state model of the main gel to liquid crystalline phase transition in lipid bilayers. Experimental data for a variety of diacylphosphatidylcholines and their derivatives have been fit by least squares to the two-state expression to within currently achievable measurement error. Numerical techniques have been developed for placing bounds on the parameters of the two-state model in situations of sparse data in the phase transition region. By fitting the model to the measured spectroscopic data, estimates of the extent of cooperativity in the phase transition can be obtained in a systematic manner. [Gaithersburg, MD] : U.S. Dept. of Commerce, National Institute of Standards and Technology 1987 1987-04-01 /pmc/articles/PMC5286997/ http://dx.doi.org/10.6028/jres.092.012 Text en https://creativecommons.org/publicdomain/zero/1.0/ The Journal of Research of the National Bureau of Standards is a publication of the U.S. Government. The papers are in the public domain and are not subject to copyright in the United States. Articles from J Res may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.
spellingShingle Article
Kirchhoff, William H.
Levin, Ira W.
Description of the Thermotropic Behavior Of Membrane Bilayers In Terms of Raman Spectral Parameters: A Two-State Model
title Description of the Thermotropic Behavior Of Membrane Bilayers In Terms of Raman Spectral Parameters: A Two-State Model
title_full Description of the Thermotropic Behavior Of Membrane Bilayers In Terms of Raman Spectral Parameters: A Two-State Model
title_fullStr Description of the Thermotropic Behavior Of Membrane Bilayers In Terms of Raman Spectral Parameters: A Two-State Model
title_full_unstemmed Description of the Thermotropic Behavior Of Membrane Bilayers In Terms of Raman Spectral Parameters: A Two-State Model
title_short Description of the Thermotropic Behavior Of Membrane Bilayers In Terms of Raman Spectral Parameters: A Two-State Model
title_sort description of the thermotropic behavior of membrane bilayers in terms of raman spectral parameters: a two-state model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286997/
http://dx.doi.org/10.6028/jres.092.012
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