Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation

The mammalian nuclear envelope (NE) can develop complex dynamic membrane-bounded invaginations in response to both physiological and pathological stimuli. Since the formation of these nucleoplasmic reticulum (NR) structures can occur during interphase, without mitotic NE breakdown and reassembly, so...

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Detalles Bibliográficos
Autores principales: Drozdz, Marek Mateusz, Vaux, David John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287099/
https://www.ncbi.nlm.nih.gov/pubmed/27797635
http://dx.doi.org/10.1080/19491034.2016.1252893
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author Drozdz, Marek Mateusz
Vaux, David John
author_facet Drozdz, Marek Mateusz
Vaux, David John
author_sort Drozdz, Marek Mateusz
collection PubMed
description The mammalian nuclear envelope (NE) can develop complex dynamic membrane-bounded invaginations in response to both physiological and pathological stimuli. Since the formation of these nucleoplasmic reticulum (NR) structures can occur during interphase, without mitotic NE breakdown and reassembly, some other mechanism must drive their development. Here we consider models for deformation of the interphase NE, together with the evidence for their potential roles in NR formation.
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spelling pubmed-52870992017-02-14 Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation Drozdz, Marek Mateusz Vaux, David John Nucleus Commentary The mammalian nuclear envelope (NE) can develop complex dynamic membrane-bounded invaginations in response to both physiological and pathological stimuli. Since the formation of these nucleoplasmic reticulum (NR) structures can occur during interphase, without mitotic NE breakdown and reassembly, some other mechanism must drive their development. Here we consider models for deformation of the interphase NE, together with the evidence for their potential roles in NR formation. Taylor & Francis 2016-10-31 /pmc/articles/PMC5287099/ /pubmed/27797635 http://dx.doi.org/10.1080/19491034.2016.1252893 Text en © 2017 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Commentary
Drozdz, Marek Mateusz
Vaux, David John
Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation
title Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation
title_full Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation
title_fullStr Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation
title_full_unstemmed Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation
title_short Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation
title_sort shared mechanisms in physiological and pathological nucleoplasmic reticulum formation
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287099/
https://www.ncbi.nlm.nih.gov/pubmed/27797635
http://dx.doi.org/10.1080/19491034.2016.1252893
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AT vauxdavidjohn sharedmechanismsinphysiologicalandpathologicalnucleoplasmicreticulumformation

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