Loss of maternal Trim28 causes male-predominant early embryonic lethality

Global DNA demethylation is a hallmark of embryonic epigenetic reprogramming. However, embryos engage noncanonical DNA methylation maintenance mechanisms to ensure inheritance of exceptional epigenetic germline features to the soma. Besides the paradigmatic genomic imprints, these exceptions remain...

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Detalles Bibliográficos
Autores principales: Sampath Kumar, Abhishek, Seah, Michelle K.Y., Ling, Ka Yi, Wang, Yaju, Tan, Joel H.L., Nitsch, Sandra, Lim, Shu Ly, Lorthongpanich, Chanchao, Wollmann, Heike, Low, Diana H.P., Guccione, Ernesto, Messerschmidt, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287108/
https://www.ncbi.nlm.nih.gov/pubmed/28115466
http://dx.doi.org/10.1101/gad.291195.116

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