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microRNA target prediction programs predict many false positives

According to the current view, each microRNA regulates hundreds of genes. Computational tools aim at identifying microRNA targets, usually selecting evolutionarily conserved microRNA binding sites. While the false positive rates have been evaluated for some prediction programs, that information is r...

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Detalles Bibliográficos
Autores principales:	Pinzón, Natalia, Li, Blaise, Martinez, Laura, Sergeeva, Anna, Presumey, Jessy, Apparailly, Florence, Seitz, Hervé
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287229/ https://www.ncbi.nlm.nih.gov/pubmed/28148562 http://dx.doi.org/10.1101/gr.205146.116

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