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Numerical and spatial patterning of yeast meiotic DNA breaks by Tel1

The Spo11-generated double-strand breaks (DSBs) that initiate meiotic recombination are dangerous lesions that can disrupt genome integrity, so meiotic cells regulate their number, timing, and distribution. Mechanisms of this regulation remain poorly understood. Here, we use Spo11-oligonucleotide co...

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Detalles Bibliográficos
Autores principales: Mohibullah, Neeman, Keeney, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287233/
https://www.ncbi.nlm.nih.gov/pubmed/27923845
http://dx.doi.org/10.1101/gr.213587.116