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A Novel Immunosuppressor, (5R)-5-Hydroxytriptolide, Alleviates Movement Disorder and Neuroinflammation in a 6-OHDA Hemiparkinsonian Rat Model

Parkinson’s disease (PD) is one of the most common age-related neurodegenerative diseases. Promising therapies for PD still need to be explored. Immune dysfunction has been found to be involved in PD pathogenesis. Here, a novel immunosuppressor, (5R)-5-hydroxytriptolide (LLDT8), was used to treat 6-...

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Detalles Bibliográficos
Autores principales: Su, Ruijun, Sun, Min, Wang, Wei, Zhang, Jianliang, Zhang, Li, Zhen, Junli, Qian, Yanjing, Zheng, Yan, Wang, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287386/
https://www.ncbi.nlm.nih.gov/pubmed/28203480
http://dx.doi.org/10.14336/AD.2016.0929