Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice

PURPOSE: Increased inflammatory mediator levels are reported in diabetic retinopathy. We previously reported that β-adrenergic receptor agonists reduced inflammatory mediators in the diabetic retina; however, these agents cannot be given systemically. Here, we investigated whether Epac1 is key to th...

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Detalles Bibliográficos
Autores principales: Liu, Li, Jiang, Youde, Chahine, Adam, Curtiss, Elizabeth, Steinle, Jena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287445/
https://www.ncbi.nlm.nih.gov/pubmed/28210097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287445/
https://www.ncbi.nlm.nih.gov/pubmed/28210097

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