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Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy
DNA is the well-known molecular target of current platinum-based anticancer drugs; consequently, their clinical use is severely restricted by their systemic toxicities and drug resistance originating from non-selective DNA damage. Various strategies have been developed to circumvent the shortcomings...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287571/ https://www.ncbi.nlm.nih.gov/pubmed/27381943 http://dx.doi.org/10.1016/j.bcp.2016.06.019 |