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The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging

Mammalian target of rapamycin complex 2 (mTORC2), one of two different enzymatic complexes of mTOR, regulates a diverse set of substrates including Akt. mTOR pathway is one of well-known mediators of aging process, however, its role in skin aging has not been determined. Skin aging can be induced by...

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Detalles Bibliográficos
Autores principales: Choi, Yeon Ja, Moon, Kyoung Mi, Chung, Ki Wung, Jeong, Ji Won, Park, Daeui, Kim, Dae Hyun, Yu, Byung Pal, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288141/
https://www.ncbi.nlm.nih.gov/pubmed/27486771
http://dx.doi.org/10.18632/oncotarget.10943