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KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth
Krüppel-like factor 4 (KLF4) is a transcription factor that contributes to diverse cellular processes and serves as a tumor suppressor or oncogene in various cancers. Previously, we have reported on the tumor suppressive function of KLF4 in lung cancer; however, its precise regulatory mechanism rema...
Autores principales: | Hu, Wenxian, Jia, Yunlu, Xiao, Xiangsheng, Lv, Kezhen, Chen, Yongxia, Wang, Linbo, Luo, Xiao, Liu, Tianze, Li, Wenbin, Li, Yixin, Zhang, Changlin, Yu, Zhenglong, Huang, Wenlin, Sun, Bing, Deng, Wu-guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288155/ https://www.ncbi.nlm.nih.gov/pubmed/27153563 http://dx.doi.org/10.18632/oncotarget.9141 |
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