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Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer
Accumulating data suggests that the initiation and progression of human breast tumors is fueled by a rare subpopulation of tumor cells, termed breast tumor-initiating cells (BTIC), which resist radiotherapy and chemotherapy. Consequently, therapies that abrogate BTIC activity are needed to achieve d...
Autores principales: | Hallett, Robin M., Girgis-Gabardo, Adele, Gwynne, William D., Giacomelli, Andrew O., Bisson, Jennifer N.P., Jensen, Jeremy E., Dvorkin-Gheva, Anna, Hassell, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288174/ https://www.ncbi.nlm.nih.gov/pubmed/27447971 http://dx.doi.org/10.18632/oncotarget.10614 |
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