Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small molecules

Heat shock protein 27 (HSP27, HSPB1) is an anti-apoptotic protein characterized for its tumorigenic and metastatic properties, and now referenced as a major therapeutic target in many types of cancer. The biochemical properties of HSP27 rely on a structural oligomeric and dynamic organization that i...

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Detalles Bibliográficos
Autores principales: Kim, Jee Hye, Jung, Ye Jin, Choi, Byeol, Lee, Na Lim, Lee, Hae Jun, Kwak, Soo Yeon, Kwon, Youngjoo, Na, Younghwa, Lee, Yun-Sil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288177/
https://www.ncbi.nlm.nih.gov/pubmed/27449291
http://dx.doi.org/10.18632/oncotarget.10629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288177/
https://www.ncbi.nlm.nih.gov/pubmed/27449291
http://dx.doi.org/10.18632/oncotarget.10629

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