Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy

We have recently shown that caspase-8 is a new substrate of Polo-like kinase 3 (Plk3) that phosphorylates the protein on residue T273 thereby promoting its pro-apoptotic function. In the present study we aimed to investigate the clinical relevance of Plk3 expression and phosphorylation of caspase-8...

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Detalles Bibliográficos
Autores principales: Rödel, Franz, Martin, Daniel, Helmke, Christina, Balermpas, Panagiotis, Fokas, Emmanouil, Wieland, Ulrike, Rave-Fränk, Margret, Kitz, Julia, Matthess, Yves, Raab, Monika, Strebhardt, Klaus, Rödel, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288191/
https://www.ncbi.nlm.nih.gov/pubmed/27462786
http://dx.doi.org/10.18632/oncotarget.10801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288191/
https://www.ncbi.nlm.nih.gov/pubmed/27462786
http://dx.doi.org/10.18632/oncotarget.10801

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