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The mitotic tensegrity guardian tau protects mammary epithelia from katanin-like1-induced aneuploidy

The microtubule associated-protein tau has been identified as an effective positive prognostic indicator in breast cancer. To explore the physiological function of tau in early carcinogenesis, endogenous tau was knocked down in primary cultured human mammary epithelial cells. This resulted in chromo...

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Detalles Bibliográficos
Autores principales: Sudo, Haruka, Nakajima, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288216/
https://www.ncbi.nlm.nih.gov/pubmed/27447563
http://dx.doi.org/10.18632/oncotarget.10728