Characteristics of human papillomaviruses infection in men with genital warts in Shanghai

Human papillomaviruses (HPV) infected men causes continued transmission of HPV to women. The prevalence of 15 high-risk HPV strains (HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66 and 68) and 6 low-risk HPV strains (HPV6, 11, 42, 43, 44 and CP8304) were evaluated in 935 males with genital...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xiaogang, Li, Liang, Lai, Yongxian, Liu, Qinxiu, Yan, Jianna, Tang, Yichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288230/
https://www.ncbi.nlm.nih.gov/pubmed/27270315
http://dx.doi.org/10.18632/oncotarget.9708
_version_ 1782504293072371712
author Chen, Xiaogang
Li, Liang
Lai, Yongxian
Liu, Qinxiu
Yan, Jianna
Tang, Yichen
author_facet Chen, Xiaogang
Li, Liang
Lai, Yongxian
Liu, Qinxiu
Yan, Jianna
Tang, Yichen
author_sort Chen, Xiaogang
collection PubMed
description Human papillomaviruses (HPV) infected men causes continued transmission of HPV to women. The prevalence of 15 high-risk HPV strains (HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66 and 68) and 6 low-risk HPV strains (HPV6, 11, 42, 43, 44 and CP8304) were evaluated in 935 males with genital warts. Of the 447 (447/935, 47.8%) HPV DNA positive subjects, 230 (24.6%), 356 (38.1%) and 139 (14.9%) were infected by high-risk, low-risk and both high and low-risk HPV respectively. Of the 356 low-risk HPV infected subjects, 333(93.5%) were infected by single HPV strain; 203 (57.0%), 147 (41.3%), 24 (6.7%) and 5 (1.4%) were infected with HPV genotype 6, 11, CP8304 and 44 respectively; population with age ≤ 20 showed the highest infection rate. High-risk HPV are also highly prevalent in our patients, genotype 16, 58, 51, 39, 52 and 53 are the top five prevalent genotypes with infection rates of 27.4%, 18.7%, 14.3%, 13.9%, 12.6% and 12.6% respectively; only 68.3% subjects were sole infection; subjects with 41 ≤ age ≤ 50 showed the highest infection rate. Both high and low-risk HPV are highly prevalent in men with genital warts, its impact on women HPV control and prevention need further evaluation.
format Online
Article
Text
id pubmed-5288230
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Impact Journals LLC
record_format MEDLINE/PubMed
spelling pubmed-52882302017-02-07 Characteristics of human papillomaviruses infection in men with genital warts in Shanghai Chen, Xiaogang Li, Liang Lai, Yongxian Liu, Qinxiu Yan, Jianna Tang, Yichen Oncotarget Clinical Research Paper Human papillomaviruses (HPV) infected men causes continued transmission of HPV to women. The prevalence of 15 high-risk HPV strains (HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66 and 68) and 6 low-risk HPV strains (HPV6, 11, 42, 43, 44 and CP8304) were evaluated in 935 males with genital warts. Of the 447 (447/935, 47.8%) HPV DNA positive subjects, 230 (24.6%), 356 (38.1%) and 139 (14.9%) were infected by high-risk, low-risk and both high and low-risk HPV respectively. Of the 356 low-risk HPV infected subjects, 333(93.5%) were infected by single HPV strain; 203 (57.0%), 147 (41.3%), 24 (6.7%) and 5 (1.4%) were infected with HPV genotype 6, 11, CP8304 and 44 respectively; population with age ≤ 20 showed the highest infection rate. High-risk HPV are also highly prevalent in our patients, genotype 16, 58, 51, 39, 52 and 53 are the top five prevalent genotypes with infection rates of 27.4%, 18.7%, 14.3%, 13.9%, 12.6% and 12.6% respectively; only 68.3% subjects were sole infection; subjects with 41 ≤ age ≤ 50 showed the highest infection rate. Both high and low-risk HPV are highly prevalent in men with genital warts, its impact on women HPV control and prevention need further evaluation. Impact Journals LLC 2016-05-30 /pmc/articles/PMC5288230/ /pubmed/27270315 http://dx.doi.org/10.18632/oncotarget.9708 Text en Copyright: © 2016 Chen et al. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Clinical Research Paper
Chen, Xiaogang
Li, Liang
Lai, Yongxian
Liu, Qinxiu
Yan, Jianna
Tang, Yichen
Characteristics of human papillomaviruses infection in men with genital warts in Shanghai
title Characteristics of human papillomaviruses infection in men with genital warts in Shanghai
title_full Characteristics of human papillomaviruses infection in men with genital warts in Shanghai
title_fullStr Characteristics of human papillomaviruses infection in men with genital warts in Shanghai
title_full_unstemmed Characteristics of human papillomaviruses infection in men with genital warts in Shanghai
title_short Characteristics of human papillomaviruses infection in men with genital warts in Shanghai
title_sort characteristics of human papillomaviruses infection in men with genital warts in shanghai
topic Clinical Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288230/
https://www.ncbi.nlm.nih.gov/pubmed/27270315
http://dx.doi.org/10.18632/oncotarget.9708
work_keys_str_mv AT chenxiaogang characteristicsofhumanpapillomavirusesinfectioninmenwithgenitalwartsinshanghai
AT liliang characteristicsofhumanpapillomavirusesinfectioninmenwithgenitalwartsinshanghai
AT laiyongxian characteristicsofhumanpapillomavirusesinfectioninmenwithgenitalwartsinshanghai
AT liuqinxiu characteristicsofhumanpapillomavirusesinfectioninmenwithgenitalwartsinshanghai
AT yanjianna characteristicsofhumanpapillomavirusesinfectioninmenwithgenitalwartsinshanghai
AT tangyichen characteristicsofhumanpapillomavirusesinfectioninmenwithgenitalwartsinshanghai