Cargando…
Activation of the complement cascade enhances motility of leukemic cells by downregulating expression of HO-1
As a crucial arm of innate immunity, the complement cascade (ComC) is involved both in mobilization of normal hematopoietic stem/progenitor cells (HSPCs) from bone marrow (BM) into peripheral blood and in their homing to BM. Despite the fact that ComC cleavage fragments alone do not chemoattract nor...
Autores principales: | Abdelbaset-Ismail, A, Borkowska-Rzeszotek, S, Kubis, E, Bujko, K, Brzeźniakiewicz-Janus, K, Bolkun, L, Kloczko, J, Moniuszko, M, Basak, G W, Wiktor-Jedrzejczak, W, Ratajczak, M Z |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288274/ https://www.ncbi.nlm.nih.gov/pubmed/27451975 http://dx.doi.org/10.1038/leu.2016.198 |
Ejemplares similares
-
Bioactive Phospholipids Enhance Migration and Adhesion of Human Leukemic Cells by Inhibiting Heme Oxygenase 1 (HO-1) and Inducible Nitric Oxygenase Synthase (iNOS) in a p38 MAPK-Dependent Manner
por: Abdelbaset-Ismail, Ahmed, et al.
Publicado: (2018) -
The Complement Cascade as a Mediator of Human Malignant Hematopoietic Cell Trafficking
por: Lenkiewicz, Anna, et al.
Publicado: (2019) -
Novel Evidence That Alternative Pathway of Complement Cascade Activation is Required for Optimal Homing and Engraftment of Hematopoietic Stem/progenitor Cells
por: Adamiak, Mateusz, et al.
Publicado: (2022) -
NLRP3 inflammasome couples purinergic signaling with activation of the complement cascade for the optimal release of cells from bone marrow
por: Ratajczak, Mariusz Z., et al.
Publicado: (2019) -
Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells
por: Abdelbaset-Ismail, Ahmed, et al.
Publicado: (2015)